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Systemic Enzymes: Finding your “Activation” dose.
by Dr. William Wong, ND, PhD


When a Systemic Enzyme “kicks in”’ there will be no doubt in your mind that it is working! The activation dose is the amount of enzymes you need to take in order to feel a benefit from the product. Normally, the recommended dosage given on the label is meant as a maintenance dose for those consumers with minor complaints (note: this does not apply to Zymessence™) . Consumers with Fibromyalgia, Chronic Fatigue, Arthritis, Auto Immune Conditions, Fibrosis complaints and Inflammation symptoms need to find the dose at which they begin to feel better. They can then maintain that dose or after 3 months try to reduce the dose and see if the benefits are still felt.

There is no toxicity from enzymes, (no LD-50). Some customers who have suffered accidents have been placed on 10 Systemic Enzyme capsules 3 times a day by their doctors for a few weeks until the bulk of their inflammation and its resultant pain are gone. Then they are brought down to a much lower maintenance dose to prevent the formation of scar tissue.

Hemophiliacs and those on prescription blood thinners should not use this or any other systemic enzyme as the enzymes help the drugs to work better and may overly thin the blood. Although Type 3 Hemophiliacs have used systemic enzymes with no problem of overly thinning the blood. Hemophiliacs do need to be cautious if using systemic enzymes and they should never use Nattokinase as that enzyme has no feed-back mechanism to know when to stop lysing away blood fibrin.

How to find the right dose for you:

With Zymessence™: begin taking 1 caplet daily. If 1 (one) does not address your inflammatory issues in two (2) days, try 2 per day. Most users of Zymessence™ find relief between 2 and 3 caplets per day. Rarely does anyone need more than 4 caplets a day.

With all other systemic enzyme blends:

With encapsulated systemic enzyme blends, start taking 3 capsules 3 times a day, in-between meals. If in 3 days no benefits are felt, increase the dose to 4 capsules 3 times a day, for 3 days. Continue increasing the number of capsules taken until a benefit is felt. Most will feel the enzymes kick-in somewhere between 3 and 5, 3 times a day. Some users need up to 30 to 45 per day. Note: Enterically coated systemic enzyme capsules will work at lower doses due to superior survival of the enzymes through the stomach acids.

With tableted systemic enzyme blends, start with 5 tablets 3 times per day, in-between meals. If in 3 days no benefits are felt, increase the dose to 4 capsules 3 times a day, for 3 days. Continue increasing the number of tablets taken until a benefit is felt. Many people need 40 to 80 tablets per day for inflammation relief.


Medical Disclaimer: We believe that the role of nutrition is important to good health, however, this web site is for informational purposes only and is not intended to be a substitute for professional medical advice. Our goal is to provide you, the seeker, with the information necessary for you to make important nutritional and self-help decisions. We strongly suggest that you share any products you decide to use with your health care professional for optimal individual health benefits. Women who are planning on becoming pregnant or who are pregnant should not take any supplements without consulting their physician first. Information and statements on this website regarding dietary supplements have not been evaluated by the Food and Drug Administration, and are not intended to diagnose, treat, cure, mitigate or prevent any disease or health condition.
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